Jacobsen syndrome (JS) is a rare, inherited disorder, characterized by facial and skull dysmorphism,\nmental retardation, and platelet abnormalities. Paris-Trousseau syndrome (PTS) is a\nplatelet function disorder that may be encountered in patients affected by JS. PTS is manifested by\na mild lifelong bleeding tendency. Morphologically, the presence of large fused platelet alpha granules\nis characteristic. We present a case of Jacobsen syndrome in a child and highlight the typical\nmorphologic and ultra structure findings of platelets.
Loading....